NTP Requests Information on Substances Nominated for Inclusion in Report on Carcinogens

Published October 14, 2015

The National Toxicology Program (NTP) is requesting information on six substances that have been nominated for possible review for future editions of the Report on Carcinogens (RoC). NTP plans to use this information to identify nominated substances to propose for formal evaluation for the RoC. The nominated substances include flame retardants tetrabromobisphenol A and pentabromodiphenyl ether mixture; water disinfection byproducts dibromoacetonitrile and di- and tri-haloacetic acids; fluoride; and vinylidene chloride. The list is available on NTP’s website and in a notice in the Federal Register.

Specifically, NTP requests information for each substance on the following topics:

  • data on current production, use patterns, and human exposure
  • information about published, ongoing, or planned studies related to evaluating carcinogenicity
  • scientific issues important for assessing carcinogenicity of the substance
  • names of scientists with expertise or knowledge about the substance

NTP’s Office of Health Assessment and Translation is considering additional substances and exposure circumstances for evaluation of non-cancer health outcomes, including neonicotinoid pesticides, mountaintop removal mining’s health impacts on surrounding communities, and fluoride (for developmental neurotoxicity and endocrine disruption).

The deadline to submit information is Nov. 6. Information can be submitted electronically via NTP’s website.

The RoC is published biennially and includes information about substances in the environment that potentially put people at increased risk for cancer in the United States. The 13th RoC is the latest edition of the publication.