July 7, 2022

New Toxicological Profile Published for Acetone

A new final toxicological profile for acetone is available from the Agency for Toxic Substances and Disease Registry. According to ATSDR, workers in industries such as commercial painting, plastic manufacturing, household cleaning, and beauty salons may be exposed to higher levels of acetone in the air in the workplace. The agency’s information sheet on acetone advises that a strong scent of acetone and irritation of the eyes, nose, and throat are “warning signs of moderate exposure.” Health effects associated with breathing high amounts of acetone during a short period of time can include headaches, confusion, nausea, racing pulse, and unconsciousness, and skin contact with acetone can cause dryness, irritation, and cracking. Studies of long-term acetone exposure among animals have shown effects such as kidney, liver, and nerve damage; birth defects; and male infertility. ATSDR notes that it is not known if long-term exposure to the chemical affects people similarly.

New final toxicological profiles are also available for the insecticides aldrin and dieldrin; chlorophenols, a group of synthetic chemicals with uses in several industries and products; and 3,3’-dichlorobenzidine, a chemical used in the production of dyes and pigments in products such as textiles, plastics, rubbers, and leather.

ATSDR toxicological profiles characterize the toxicology and adverse health effects information for hazardous substances. The peer-reviewed profiles identify and review the key literature describing substances’ toxicological properties. Information on substances’ potential for human exposure; chemical and physical properties; regulations and guidelines; and production, import, use, and disposal can also be found in ATSDR’s toxicological profiles. A full list of toxic substances with published profiles is available on the agency’s website.