March 14, 2024 / Dan L. Christensen

Complying with the Surface Sampling Requirements of USP 800

Sponsored by Bureau Veritas

In the intricate world of healthcare and pharmacy operations, ensuring a safe environment for both patients and staff is paramount. The handling of hazardous drugs (HDs) presents a unique set of challenges, particularly in preventing contamination and exposure. The United States Pharmacopeia (USP) Chapter 800 provides standards for the safe handling of HDs to minimize the risks of exposure and contamination. A critical aspect of adhering to these standards involves surface sampling, a process that ensures work environments are free from HD residues. This introduction to the surface sampling requirements of USP 800 also explores the innovative solution provided by the Bureau Veritas ChemoAlert surface sampling kit for hazardous drug testing.

USP 800 outlines the need for rigorous environmental quality and control, including surface sampling to detect contamination by hazardous drugs in healthcare settings. Surface sampling is essential for assessing the effectiveness of cleaning procedures and ensuring that areas where hazardous drugs are stored, prepared, and administered maintain the required safety levels. These requirements highlight the importance of regular monitoring and evaluation to protect healthcare workers, patients, and the environment from the potential risks posed by HD exposure.

The ChemoAlert surface sampling kit stands out as a dedicated solution designed to meet the stringent requirements of USP 800 for hazardous drug testing. It provides a comprehensive toolset for the safe and effective sampling of surfaces that may have been contaminated with hazardous drugs. The kit includes all necessary components for collecting samples from various surfaces, ensuring that healthcare facilities can monitor and maintain a safe environment for both staff and patients.

Using the ChemoAlert surface sampling kit is straightforward and designed to ensure accurate and reliable results:

  1. Preparation: Before sampling, wear appropriate personal protective equipment to minimize the risk of exposure. Ensure that the area to be sampled is properly identified and prepared.
  2. Sampling: Use one of the 10 swabs provided in the kit to gently swab the designated area with a predefined template. The swabs and wetting agent are designed to collect residues effectively without damaging surfaces.
  3. Storage and shipping: After collecting the samples, they should be stored in the provided containers and refrigerated until they are shipped. It is crucial to ship the samples cold, a unique requirement of the ChemoAlert kit, to preserve the integrity of the samples for accurate analysis.
  4. Analysis: Upon receipt, the samples are analyzed in our specialized laboratory to identify and quantify up to 19 hazardous drug residues per sample from a library of over 1,000 HDs.

The ChemoAlert surface sampling kit remains the superior solution in the landscape of hazardous drug testing, offering an efficient and reliable method for healthcare facilities to comply with USP 800 requirements. By ensuring safe handling processes of hazardous drugs and minimizing the risk of contamination and exposure, ChemoAlert supports the health and safety of healthcare workers and patients alike.

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Dan L. Christensen

Dan L. Christensen is a recognized voice in the occupational health field, certified in both industrial hygiene and safety. He currently serves as director of industrial hygiene sales for Bureau Veritas North America.


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