The International Agency for Research on Cancer (IARC) has classified welding fumes and UV radiation from welding as Group 1 carcinogens, the agency’s designation for agents that carry sufficient evidence of carcinogenicity in humans. When IARC previously assessed the carcinogenicity of welding fumes in 1989, the agency classified them in Group 2B as “possibly carcinogenic to humans.” At the time, IARC based its classification on “limited evidence in human beings” and “inadequate evidence” in experimental animals. According to the agency, its new classification for welding fumes is based on “substantial new evidence” from observational and experimental studies. UV radiation from welding was previously classified as a Group 1 carcinogen in an IARC monograph published in 2012.
IARC also evaluated two related chemicals, molybdenum trioxide and indium tin oxide. Both were classified in Group 2B as chemicals that are possibly carcinogenic to humans. IARC’s classification is based on “sufficient evidence” of the chemicals’ carcinogenicity in experimental animals.
A summary of IARC’s evaluation is available online in The Lancet Oncology. The full article is available free of charge to registered users (registration is also free).
IARC’s detailed assessments will be published later in Volume 118 of the IARC Monographs. IARC monographs identify and evaluate environmental factors that can increase carcinogenic risks to humans. IARC is the specialized cancer agency of the World Health Organization, and government agencies worldwide use its monographs as scientific support for their actions to prevent exposure to potential carcinogens.
In June, the IARC working group will meet to review some chemicals in food and consumer products. Pyridine and vinylidene chloride are among the chemicals on the agency’s preliminary list of agents to be reviewed during that meeting. IARC is also planning to update its evaluation of the carcinogenicity of benzene; a meeting regarding benzene is set for October.